Medicine Recommendations

Treating chronic hyperuricaemia in people with gout (NICE TA506)

NICE TA506 - Lesinurad for treating chronic hyperuricaemia in people with gout

Breast cancer

NICE guideline NG101: Early and locally advanced breast cancer: diagnosis and management

Roundworm infections (unlicensed)

Epilepsy

MHRA Drug Safety Update - Antiepileptic drugs: updated advice on switching between different manufacturers’ products   

Management for prolonged seizures or status epilepticus in palliative and end of life care

Epilepsy

MHRA Drug Safety Update - Antiepileptic drugs: updated advice on switching between different manufacturers’ products

Care in the last weeks or days of life - Nausea and vomiting in the last days of life AND Agitation/terminal restlessness in the last days of life

Nausea and vomiting

Opioid-induced nausea and vomiting

Schizophrenia (Existing Patients)

The colour classification was determined as part of the collaborative work between LCFT and Medicines Management leads. Local pathways and patient safety were taken into consideration.

Schizophrenia (New Patients)

The colour classification was determined as part of the collaborative work between LCFT and Medicines Management leads. Local pathways and patient safety were taken into consideration.

Contraception

MHRA Drug Safety Update - Intrauterine contraception: uterine perforation—updated information on risk factors

MHRA Drug Safety Update - Levonorgestrel-releasing intrauterine systems: prescribe by brand name

Complex neuropathic pain

Use outside of the license of post-herpetic neuralgia for the treatment of localised neuropathic pain with predominance of allodynia and/or hyperalgesia and dysesthesias unresponsive to other neuropathic agents

Post Herpetic Neuralgia (as per LSCMMG Guidelines)

Treatment of primary premature ejaculation in adult men

 Moderate to severe irritable bowel syndrome with constipation

*FOR WEST LANCASHIRE ONLY* - Green for Second line option for the symptomatic treatment of moderate to severe irritable bowel syndrome with constipation (IBS-C) in adults

Type 2 diabetes

For the treatment of pneumonia or complicated skin and soft tissue infections on the recommendation of a microbiologist when used for up to 14-days

**Please refer to attached prescriber information sheet for more detail prior to prescribing**

Treating moderate to severe symptoms of uterine fibroids (NICE TA996)

NICE TA996 - Linzagolix for treating moderate to severe symptoms of uterine fibroids

Add-on treatment for refractory hypothyroidism despite adequate replacement with levothyroxine – new patients.

Liothyronine for the treatment of acute conditions where thyroid replacement is needed rapidly, for a limited period and/or where a drug with shorter half-life is required.