Medicine Recommendations

Type 2 diabetes mellitus

Type 2 diabetes mellitus [in combination with metformin]

Type 1 and type 2 diabetes mellitus

Type 1 and type 2 diabetes mellitus

Treatment of diabetes mellitus in adults

Hypothyroidism

Type 1 and type 2 diabetes mellitus

Type 2 diabetes

Treating moderate to severe symptoms of uterine fibroids (NICE TA996)

NICE TA996 - Linzagolix for treating moderate to severe symptoms of uterine fibroids

Add-on treatment for refractory hypothyroidism despite adequate replacement with levothyroxine – new patients.

Liothyronine for the treatment of acute conditions where thyroid replacement is needed rapidly, for a limited period and/or where a drug with shorter half-life is required.

Resistant depression

**This entry is under review**

Liothyronine monotherapy for the management of chronic hypothyroidism – primary and secondary care

Add-on treatment for refractory hypothyroidism – existing patients.

Liothyronine therapy commenced in the private sector

Type 2 diabetes mellitus (NICE NG28)

NICE NG28 - Type 2 diabetes in adults: management

NICE TA664 - For managing overweight and obesity

Type 2 diabetes mellitus

Suitable for initiation in primary care in line with restrictions (see background paragraph)

Reduction in the risk or delay of the onset of type 2 diabetes mellitus in adult, overweight patients with implied Glucose Tolerance and/or increased HbA1C who are at high risk for developing overt type 2 diabetes mellitus and still progressing towards type 2 diabetes mellitus despite implementation of intensive lifestyle change for 3-6 months

Treatment of type 2 diabetes mellitus, particularly in overweight patients, when dietary management and exercise alone does not result in adequate glycaemic control