Medicine Recommendations

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Ketamine (oral use)

Date Posted: 20 - May - 2021

BNF chapter: Anaesthesia

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Chronic Non-Cancer Pain (off-label use) in adults

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Ketamine (Parenteral Use)

Date Posted: 01 - Oct - 2019

BNF chapter: Anaesthesia

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Chronic Non-Cancer Pain (off-label use) in adults

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Ketovite

Date Posted: 01 - May - 2018

BNF chapter: Blood and Nutrition

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Patients on haemodialysis

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Lacosamide

Date Posted: 01 - Oct - 2014

BNF chapter: Central nervous system

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Epilepsy

MHRA Drug Safety Update - Antiepileptic drugs: updated advice on switching between different manufacturers’ products

Palliative Use Only

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Lactulose

Date Posted: 06 - Apr - 2022

BNF chapter: Gastro-intestinal system

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Constipation

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Lamotrigine

Date Posted: 01 - May - 2013

BNF chapter: Central nervous system

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Bipolar disorder

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Lamotrigine

Date Posted: 01 - Oct - 2014

BNF chapter: Central nervous system

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Epilepsy

MHRA Drug Safety Update - Antiepileptic drugs: updated advice on switching between different manufacturers’ products

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Lanreotide

Date Posted: 01 - Oct - 2019

BNF chapter: Immune system and Malignant Disease

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Unlicensed use in non-acute treatment of recurrent gastrointestinal bleeding disorders (including angiodysplasia, small bowel dysplasia, gastric antral vascular ectasia, haemorrhagic telangiectasia)

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Lanreotide

Date Posted: 05 - Mar - 2020

BNF chapter: Immune system and Malignant Disease

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Unlicensed use for orthostatic intolerance disorders e.g. postural orthostatic tachycardia syndrome (PoTS)

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Lanreotide

Date Posted: 05 - Mar - 2020

BNF chapter: Immune system and Malignant Disease

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Unlicensed use in Secretory Gastrointestinal Disorders (e.g. enterocutaneous fistula, high output stoma and refractory diarrhoea)

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Lanthanum

Date Posted: 01 - May - 2013

BNF chapter: Blood and Nutrition

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Hyperphosphataemia (NICE CG157)

NICE CG157 - Hyperphosphataemia in chronic kidney disease: Management of hyperphosphataemia in patients with stage 4 or 5 chronic kidney disease

Please note Blackburn with Darwen & East Lancashire CCGs have more than one RAG status. Please consult local formulary

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Lebrikizumab

Date Posted: 22 - Oct - 2024

BNF chapter: Skin

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Treating moderate to severe atopic dermatitis in people 12 years and over (NICE TA986)

NICE TA986: Lebrikizumab for treating moderate to severe atopic dermatitis in people 12 years and over

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Leflunomide

Date Posted: 01 - May - 2013

BNF chapter: Musculoskeletal system

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Rheumatic diseases

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Lesinurad

Date Posted: 01 - Mar - 2018

BNF chapter: Musculoskeletal system

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Treating chronic hyperuricaemia in people with gout (NICE TA506)

NICE TA506 - Lesinurad for treating chronic hyperuricaemia in people with gout

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Letrozole

Date Posted: 01 - May - 2014

BNF chapter: Immune system and Malignant Disease

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Breast cancer

NICE guideline NG101: Early and locally advanced breast cancer: diagnosis and management

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Levamisole

Date Posted: 01 - Oct - 2014

BNF chapter: Infection

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Roundworm infections (unlicensed)

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Levetiracetam

Date Posted: 01 - Oct - 2014

BNF chapter: Central nervous system

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Epilepsy

MHRA Drug Safety Update - Antiepileptic drugs: updated advice on switching between different manufacturers’ products

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Levetiracetam Infusion

Date Posted: 01 - Oct - 2014

BNF chapter: Central nervous system

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Epilepsy

MHRA Drug Safety Update - Antiepileptic drugs: updated advice on switching between different manufacturers’ products

Palliative Use Only

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Levomepromazine

Date Posted: 31 - Mar - 2022

BNF chapter: Central nervous system

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Care in the last weeks or days of life - Nausea and vomiting in the last days of life AND Agitation/terminal restlessness in the last days of life

Nausea and vomiting

Opioid-induced nausea and vomiting

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Levomepromazine

Date Posted: 01 - Oct - 2016

BNF chapter: Central nervous system

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Schizophrenia (Existing Patients)

The colour classification was determined as part of the collaborative work between LCFT and Medicines Management leads. Local pathways and patient safety were taken into consideration.