Adalimumab
Indication
Second line biologic for moderate to severe active ulcerative colitis after the failure of conventional therapy (NICE TA329) and LSCMMG Recommendation
Red
Brand:
Humira®
Nice TA:
329
Commissioning responsibility:
CCG
PbR excluded:
Yes
BNF chapter:
Gastro-intestinal system
Background
In UC patients who experience intolerance, secondary failure or primary failure with a first line biologic in line with NICE TA329 or TA342, adalimumab should be used in preference to alternative TNF-alpha inhibitors where it is available.
Recommendation
LSCMMG Recommendation:
Red
Reason for decision:
Specialist medicine
Supporting documents: