Infliximab
Indication
Use in high risk patients for prevention of recurrence or upon recurrence of Crohn's Disease following surgery.
Red
Brand:
Remicade®, Inflectra®, Remsima®
Nice TA:
Commissioning responsibility:
CCG
PbR excluded:
Yes
BNF chapter:
Gastro-intestinal system
Background
In patients at high risk of recurrence (e.g. more than one resection, or penetrating or fistulising disease), prophylaxis with thiopurine should be considered where appropriate. A biologic may be considered in these high risk patients upon recurrence, or if thiopurine treatment is not tolerated i.e RED colour classification. Note: Routine use of biologic agents to prevent recurrence of CD following surgery is not recommended.
Recommendation
LSCMMG Recommendation:
Red
Reason for decision:
Specialist medicine
Supporting documents: